Kenneth D Tew Selected Research

Multiple Myeloma

11/2020	Altered redox regulation and S-glutathionylation of BiP contribute to bortezomib resistance in multiple myeloma.
1/2016	Commentary on "Proteasome Inhibitors: A Novel Class of Potent and Effective Antitumor Agents".

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Kenneth D Tew Research Topics

Disease

41	Neoplasms (Cancer) 11/2023 - 08/2001
6	Ovarian Neoplasms (Ovarian Cancer) 01/2010 - 10/2002
5	Neoplasm Metastasis (Metastasis) 10/2023 - 01/2011
3	Melanoma (Melanoma, Malignant) 11/2023 - 01/2023
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 11/2023 - 08/2005
3	Leukemia 01/2021 - 10/2009
3	Carcinogenesis 10/2020 - 01/2005
3	Prostatic Neoplasms (Prostate Cancer) 01/2019 - 12/2005
3	Lung Neoplasms (Lung Cancer) 01/2019 - 08/2005
3	Atherosclerosis 08/2012 - 04/2004
3	Alzheimer Disease (Alzheimer's Disease) 01/2012 - 01/2007
3	Carcinoma (Carcinomatosis) 01/2007 - 10/2002
2	Triple Negative Breast Neoplasms 01/2021 - 12/2017
2	Multiple Myeloma 11/2020 - 01/2016
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2018 - 04/2004
2	Fibrosis (Cirrhosis) 06/2016 - 09/2012
1	Inflammation (Inflammations) 11/2023
1	Pneumonia (Pneumonitis) 11/2023
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2021
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2021
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2021
1	Breast Neoplasms (Breast Cancer) 01/2019
1	Residual Neoplasm 12/2017
1	Lung Diseases (Lung Disease) 06/2016
1	Idiopathic Pulmonary Fibrosis 06/2016
1	Chronic Obstructive Pulmonary Disease (COPD) 02/2016
1	Papilloma (Papillomatosis) 12/2012

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 01/2023 - 01/2005
8	Glutathione Transferase (Glutathione S-Transferase)IBA 10/2023 - 10/2003
6	EnzymesIBA 01/2023 - 08/2001
5	O-(glucuronic acid 2-sulfate)-(1--3)-O-(2,5)-andydrotalitol 6-sulfateIBA 01/2023 - 08/2001
5	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2023 - 04/2004
4	Cisplatin (Platino)FDA LinkGeneric 01/2021 - 10/2002
4	CholesterolIBA 01/2018 - 01/2007
4	O(2)- (2,4- dinitro- 5- (N- methyl- N- 4- carboxyphenylamino)phenyl 1- N,N- dimethylamino)diazen- 1- ium- 1,2- diolateIBA 10/2011 - 05/2004
4	Estramustine FDA Link 01/2007 - 04/2004
3	AntioxidantsIBA 01/2023 - 10/2020
3	IsoflavonesIBA 01/2019 - 01/2016
3	ProdrugsIBA 01/2016 - 10/2002
3	Glutathione (Reduced Glutathione)IBA 12/2012 - 01/2005
3	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2011 - 01/2007
3	NOV 002IBA 01/2010 - 04/2008
3	Glutathione S-Transferase piIBA 01/2009 - 10/2002
2	Transcription Factors (Transcription Factor)IBA 11/2023 - 10/2020
2	Adenosine Triphosphate (ATP)IBA 01/2023 - 04/2008
2	Protein Isoforms (Isoforms)IBA 01/2021 - 05/2004
2	gamma-Glu-S-BzCys-PhGly diethyl ester (T.199)IBA 01/2021 - 06/2016
2	Bortezomib (Velcade)FDA Link 11/2020 - 01/2016
2	SulfurIBA 10/2020 - 01/2004
2	ME-344IBA 01/2019 - 01/2016
2	SerpinsIBA 01/2019 - 05/2012
2	SterolsIBA 01/2018 - 01/2007
2	SteroidsIBA 01/2018 - 01/2007
2	Bleomycin (Blenoxane)FDA LinkGeneric 06/2016 - 09/2012
2	LipidsIBA 08/2012 - 04/2008
2	Sulfhydryl Compounds (Thiols)IBA 02/2011 - 01/2004
2	Estradiol (Delestrogen)FDA LinkGeneric 01/2007 - 04/2004
2	TER 286 (TLK286)IBA 08/2005 - 10/2002
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 05/2004 - 04/2004
1	Dithiothreitol (Cleland's Reagent)IBA 11/2023
1	RotenoneIBA 11/2023
1	Acetylcysteine (Siran)FDA LinkGeneric 11/2023
1	Oxidants (Oxidizing Agents)IBA 11/2023
1	NF-kappa B (NF-kB)IBA 11/2023
1	microsomal glutathione S-transferase-IIBA 10/2023
1	SeleniumIBA 10/2023
1	Glutathione PeroxidaseIBA 10/2023
1	CytokinesIBA 10/2023
1	Protein Disulfide-IsomerasesIBA 01/2023
1	Levodopa (L Dopa)FDA LinkGeneric 01/2023
1	Melanins (Melanin)IBA 01/2023
1	eumelaninIBA 01/2023
1	dopachromeIBA 01/2023
1	Cyclin D3IBA 01/2021
1	Karyopherins (Importin)IBA 01/2021
1	PhosphofructokinasesIBA 01/2021
1	CXC ChemokinesIBA 01/2021
1	Chemokine ReceptorsIBA 01/2021
1	DisulfidesIBA 11/2020
1	NADP (NADPH)IBA 10/2020
1	Glutamine (L-Glutamine)FDA Link 10/2020
1	Folic Acid (Vitamin M)FDA LinkGeneric 10/2020
1	Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA 01/2019
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2019
1	Biomarkers (Surrogate Marker)IBA 01/2019
1	Epithelial Cell Adhesion MoleculeIBA 01/2019
1	triptolideIBA 12/2017
1	CaspasesIBA 06/2016
1	CollagenIBA 06/2016
1	Protein SIBA 06/2016
1	Acrolein (Aqualin)IBA 02/2016
1	Peroxynitrous Acid (Peroxynitrite)IBA 02/2016
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 02/2016
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2016
1	Cysteine (L-Cysteine)FDA Link 12/2012

Therapy/Procedure

7	Therapeutics 01/2023 - 08/2010
5	Drug Therapy (Chemotherapy) 01/2021 - 12/2005
2	Radiotherapy 03/2020 - 01/2019
1	Immunotherapy 10/2023
1	Chemoprevention 01/2017